外界激励对生物类溶致液晶的影响

吴赛博; 沈冬; 严仕凯; 张桐; 卫炳铄; 王丽玲

doi:10.3788/YJYXS20173210.0772

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外界激励对生物类溶致液晶的影响

材料科学 | 更新时间：2020-08-12

- 外界激励对生物类溶致液晶的影响
- Effects of external excitations on biological lyotropic liquid crystals
- 液晶与显示 2017年32卷第10期页码：772-782
- 作者机构：
  
  华东理工大学理学院, 上海 200237
- 作者简介：
  
  [ "吴赛博(1995-), 男, 江苏启东人, 主要从事溶致液晶与液晶光学器件方面的研究。E-mail:cyber0606@163.com" ]
  沈冬, E-mail：shen@ecust.edu.cn
- 基金信息：
  
  国家自然科学基金(61435008);华东理工大学大学生创新项目(S15073);National Natural Science Foundation of China(61435008);Student Research Project of East China University of Science and Technology(S15073)
- DOI：10.3788/YJYXS20173210.0772
  中图分类号： O753+.2
- 收稿日期：2017-04-19，
  
  录用日期：2017-5-20，
  
  纸质出版日期：2017-10-05
- 稿件说明：
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吴赛博, 沈冬, 严仕凯, 等. 外界激励对生物类溶致液晶的影响[J]. 液晶与显示, 2017,32(10):772-782.

Sai-bo WU, Dong SHEN, Shi-kai YAN, et al. Effects of external excitations on biological lyotropic liquid crystals[J]. Chinese journal of liquid crystals and displays, 2017, 32(10): 772-782.
吴赛博, 沈冬, 严仕凯, 等. 外界激励对生物类溶致液晶的影响[J]. 液晶与显示, 2017,32(10):772-782. DOI： 10.3788/YJYXS20173210.0772.

Sai-bo WU, Dong SHEN, Shi-kai YAN, et al. Effects of external excitations on biological lyotropic liquid crystals[J]. Chinese journal of liquid crystals and displays, 2017, 32(10): 772-782. DOI： 10.3788/YJYXS20173210.0772.

摘要

为了探究不同环境因素对人体生物膜结构的影响，建立了由磷脂酰胆碱分子构筑的脂质体泡囊模型。对该生物溶致液晶体系在各类外界激励下的响应进行研究。首先，观测了温度、电场、磁场不同激励作用下液晶相态的变化，并对结构的损伤破坏临界条件进行测定。其次，通过引入乙醇、石油醚等化学物质，研究了生物膜在体液环境变化前后的结构与性质差异。实验结果表明，生物膜层相的维持温区在-17.3℃~94.8℃，高温损伤临界值在45℃左右；人体电磁场短时间接触限值（4 h以内）分别为20 kV/m和40 mT；乙醇与石油醚在体液中的浓度临界值均在630 mg/100 mL以下。可见，生物膜结构只能在特定温区内维持完整；一定强度稳恒电磁场能使膜结构发生变形；无机盐离子有利于温度变化时生物膜的维持，但加剧电磁场下损伤；乙醇与石油醚能抑制膜结构形成，影响生物膜的稳定性。

Abstract

In order to explore the effects of different environmental factors on the structure of human biofilm

a lipoidal vesicle model constructed by phosphatidylcholine was established. The response of the biological lyotropic liquid crystal system under various external excitations was studied. Firstly

changes of LC phase driven by different excitations

such as temperature

electric field and magnetic field

was investigated

and the critical values or numerical ranges of the damage to the structure were measured. Then

by doping with ethanol or petroleum ether

variations of the biofilm structure and performance in different body fluid environment were analyzed. The results show that the temperature range of biofilm lamellar phase is -17.3℃~94.8℃

and the critical value of structure damage is about 45℃. The limitation of constant electromagnetic field for human exposure is 20 kV/m (4 h) and 40 mT (4 h).Critical concentrations of ethanol and petroleum ether in body fluid are both less than 630 mg/100 mL. The results show that the biofilm structure can only be maintained in a specific temperature range

and a certain strength of constant electric and magnetic field can make the membrane structure deformed. The inorganic ion is beneficial to the biofilm maintenance when temperature varies

but it increases the damage of the electromagnetic field. Ethanol and petroleum ether can inhibit the formation and the stability of biofilm.

关键词

Keywords

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